Xtandi Side Effects

adverse effects of xtandi

Are you considering taking Xtandi? It's important to be aware of the potential side effects. In this article, we will provide you with an overview of the common, gastrointestinal, hormonal, and cardiovascular effects associated with Xtandi. Additionally, we will discuss the rare and serious side effects that you should be mindful of. By understanding these potential risks, you can make informed decisions about your treatment.

Common Side Effects

When taking Xtandi, you may experience common side effects that can be managed with proper care and monitoring. It is important to be aware of these side effects and understand how to manage them effectively. One of the long-term effects of Xtandi is fatigue, which is a feeling of extreme tiredness or lack of energy. To manage fatigue, it is recommended to get plenty of rest, engage in light exercise, and eat a balanced diet. Another common side effect is hot flashes, which are sudden feelings of warmth, often accompanied by redness of the face and sweating. To manage hot flashes, wearing loose clothing, staying in a cool environment, and avoiding triggers such as spicy foods or alcohol can be helpful. It is important to communicate any side effects to your healthcare provider so that they can provide appropriate management strategies.

Gastrointestinal Effects

To continue the discussion on side effects of Xtandi, let's now explore the gastrointestinal effects that you may experience. Here are four gastrointestinal side effects that have been reported in patients taking Xtandi:

  1. Nausea: Some individuals may experience feelings of queasiness or an urge to vomit. It is important to stay hydrated and eat small, frequent meals to alleviate these symptoms.
  2. Diarrhea: Xtandi can also cause loose or watery stools. It is crucial to maintain good hygiene and drink plenty of fluids to prevent dehydration.
  3. Upset Stomach: Some patients may experience general discomfort or pain in the abdomen. This can be managed by avoiding spicy or fatty foods and eating a balanced diet.
  4. Constipation: Xtandi can occasionally cause difficulty in passing stools. Staying physically active, eating fiber-rich foods, and drinking enough water can help alleviate this symptom.

If you experience any of these gastrointestinal side effects while taking Xtandi, it is important to inform your healthcare provider for further guidance and management.

Hormonal Effects

If you are taking Xtandi, you may experience hormonal effects that can be attributed to this medication. Xtandi is known to cause endocrine disruptions and can lead to changes in the reproductive system. Endocrine disruptions refer to the interference with the normal functioning of the endocrine system, which is responsible for regulating hormones in the body. Xtandi can impact hormone levels by blocking the action of androgens, which are male sex hormones. This can result in a decrease in testosterone levels and an increase in estrogen levels. These changes can lead to various side effects such as hot flashes, decreased libido, erectile dysfunction, and breast enlargement. It is important to discuss any hormonal effects with your healthcare provider to determine the best course of action.

Cardiovascular Effects

You may experience cardiovascular effects while taking Xtandi. It is important to be aware of these potential risks and to discuss them with your healthcare provider. Here are four key points to consider regarding cardiovascular effects and management strategies:

  1. Increased risk of high blood pressure: Xtandi may cause an increase in blood pressure. Your healthcare provider may monitor your blood pressure regularly and may prescribe medications to help manage it.
  2. Risk of heart rhythm abnormalities: Xtandi can potentially cause changes in the electrical activity of the heart, leading to irregular heart rhythms. Your healthcare provider may monitor your heart rhythm through electrocardiograms (ECGs) and may adjust your medication if necessary.
  3. Potential for blood clots: Xtandi may increase the risk of blood clots, which can be dangerous if they travel to vital organs. It is important to be aware of symptoms such as swelling, pain, or redness in the legs, chest pain, shortness of breath, or sudden severe headache. If you experience any of these symptoms, seek immediate medical attention.
  4. Overall cardiovascular health management: It is important to maintain a healthy lifestyle while taking Xtandi. This includes regular exercise, a balanced diet, and avoiding smoking. Your healthcare provider may also recommend medications to manage your cholesterol levels and other cardiovascular risk factors.

Remember to discuss any concerns or questions about cardiovascular effects and management strategies with your healthcare provider to ensure your safety and well-being while taking Xtandi.

Rare and Serious Side Effects

Continuing the discussion on Xtandi's cardiovascular effects, it is important to be aware of the rare and serious side effects associated with this medication. While Xtandi is generally well-tolerated, there have been reports of rare but potentially serious neurological effects. These can include seizures, confusion, and difficulty speaking or understanding speech. If you experience any of these symptoms, it is crucial to seek medical attention immediately. Additionally, Xtandi may also have respiratory effects, such as shortness of breath or difficulty breathing. If you notice any changes in your breathing pattern or experience persistent coughing or wheezing, it is important to inform your healthcare provider. Remember, while these side effects are rare, being aware of them can help you seek prompt medical attention if needed.


In conclusion, Xtandi may cause common side effects such as fatigue and hot flashes. Gastrointestinal effects like diarrhea and nausea may also occur. Hormonal effects, including decreased sex drive and erectile dysfunction, may be experienced. Cardiovascular effects like high blood pressure and heart rhythm disturbances are rare but possible. It is important to note that Xtandi can have serious side effects, such as seizures and allergic reactions, although these are uncommon. Always consult with a healthcare professional for more information and guidance.